UC San Diego Huntington's Disease Program - a designated Center of Excellence
About Huntington's Disease
HD Center of Excellence
UC San Diego’s Huntington’s disease (HD) program is designated a Center of Excellence by the Huntingon’s Disease Society of America. Under the direction of Jody Corey-Bloom, MD, PhD, our clinical research program was among the first west of the Mississippi to receive this honor in 2000.
Huntington's disease (HD) is a genetic, degenerative brain disorder that causes uncontrolled movements, loss of ability to think and reason, and severe emotional disturbances. People with HD eventually become dependent on others for their care. The onset of the disease is typically between the ages of 30 and 50.
Age of Onset
The onset of HD typically strikes individuals during their most productive adult years, between the ages of 30 and 50, but may appear as early as the age of two or as late as the age of 70. Even within a single family the onset age of symptoms and the type of symptoms at onset may varyfrom one person to another .
More than a quarter million Americans are at risk of inheriting HD from an affected parent. An individual who inherits the gene mutation will develop the disease. HD does not skip generations. It affects all races and ethnic groups and both sexes. Each child of an HD-affected parent has a 50 percent chance of inheriting the disorder.
The HD gene was isolated in 1993. Since then, research continues to accelerate our understanding of the disease. UC San Diego Health System connects people to active clinical trials studying ways to treat HD with medications and to assess disease progression.
Some Characteristics/Symptoms of HD
- Personality changes, depression, anxiety, irritable or aggressive behavior, apathy, hallucinations, delusions or mood swings
- Unsteady gait, dance-like movements, rigidity, abnormal eye movements, problems with balance and coordination
- Slurred and/or slowed speech or difficulty swallowing
- Slowed thinking and reaction time, difficulty planning and organizing, inflexible thinking, poor decision making skills or problems with short-term memory
- Intoxicated appearance due to a combination of the above symptoms
For more information or to make an appointment, call 858-246-1254.
School of Medicine Links
San Diego Chapter of the Huntington’s Disease Society of America
Provides local support to individuals affected by HD and their families, raises public awareness and funds research towards a cure.
Huntington's Disease Society of America
The national voluntary health organization for HD. Provides resources, advocacy and funding for a cure.
Hereditary Disease Foundation
Aims to cure genetic illnesses by supporting basic biomedical research.
Stop Huntington's Disease.
Support medical research at the Neurological Institute to help end this devastating disease.