Endometriosis Research Projects
Violet Petal study
Research is underway to test a new oral investigational medication for moderate to severe pain caused by endometriosis.
To qualify you must:
- Be between age 18 to 49
- Have been surgically diagnosed with endometriosis in the last 10 years
Each individual will be evaluated to determine her Violet Petal Study participation eligibility. If you qualify, you’ll receive the investigational medication, study-related medical exams, and laboratory services at no charge. You may also be reimbursed for travel and other expenses. The purpose of the research study is to evaluate the safety and effectiveness of an investigational medication for the management of moderate to severe endometriosis-associated pain and other endometriosis-related symptoms. Visit the Violet Petal Study to learn more.
Characterization of a novel clinical marker of endometriosis
Endometriosis is a chronic, painful, progressive, inflammatory disease that has a profoundly negative effect upon women’s role performance, social functioning, emotional well-being, relationships with medical specialists, energy and employment. The lack of a suitable clinical test of endometriosis leads to significant delays in diagnosis and a low level of medical care. The health care costs associated with endometriosis are similar to or greater than other chronic diseases such as Crohn’s, diabetes, asthma, migraines and, arthritis. Sadly, women with endometriosis experience significant delays of up to 12 years before being diagnosed. The gold standard for diagnosis of endometriosis is surgery, which is invasive, expensive and has risks. This is why there is an urgent need to find other, safer and less invasive methods to make a diagnosis.
Our initial findings suggest that the levels of a protein in the blood that is involved in nerve growth that are much higher in women with endometriosis compared to healthy women. Furthermore, our results suggest that the protein levels are unaffected by the stage of the menstrual cycle and could be related to patient reports of pelvic pain. Therefore, we suggest that these proteins are potentially important tools in diagnosing endometriosis and need further study. Consequently, we are conducting a pre-clinical discovery phase project to better characterize the levels of this blood protein as a potentially useful tool in the diagnosis of endometriosis.
Comparison of contraceptive options
This study will compare contraceptive options — continuous oral contraceptives and levonorgestrel-releasing intrauterine device — in women with presumed endometriosis-related pelvic pain. If you have painful periods or pelvic pain at other times and would like to hear more about taking part in this study, please call 1-619-940-4377. One of our researchers will call you to discuss this study.