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  Red Blood Cells, Pre-Storage Leukocyte Reduced Specimen Type:
  also known as LRC Blood


Specimen requirements: Requires current Type & Screen on file
Unit of measure: N/A
Ideal sample: N/A
Absolute minimum amount: N/A
Method of collection: N/A
Transportation: N/A
Label instructions: N/A
Request test on form: MULTI LABS [Chem/Hem/UA/Tox/BB/Rheum]
Order/entry screen(s): Transfusion Services/Blood Bank
Stat frequency: N/A
Stat turn around time: N/A
Routine frequency: Daily
Must be in by: N/A
Routine turn around time: 8 Hours
Deliver the specimen to : N/A : N/A
Deliver the specimen to : N/A : N/A
Scheduling requirements : N/A
Method: N/A
Special Instructions: Indications: to support oxygen-carrying capacity, a physiologically stable medical or surgical patient whose hemoglobin is >7 g/dL generally does not require a red cell transfusion. Exceptions may be made based on compromised cardiovascular or to 10 years, and for longer intervals if there is particular need for specific units. *****red blood cells deglycerolized is the form in which cryo-preserved red cells (red blood cells frozen) are available for infusion. Red blood cells deglycerolized contain 80% or more of the red cells in the original unit, and have approximately the same expected post transfusion survival as red blood cells. This product's use should be restricted to red cells with unusual antigenic phenotypes and for autologous donations when liquid-preserved blood cannot fulfill demands. This product may also be useful to patients with clinically significant immune reactivity against IgA. This product carries the risk of intravascular hemolysis if deglycerolization has been inadequate. One donated unit can meet the needs of many patients. *red blood cells are prepared from blood collected into any of the anticoagulant-preservative solutions approved by the FDA, and separated from the plasma by centrifugation or sedimentation. Separation may be done at any time during the allowable storage interval ("shelf life"). At present, anticoagulant citrate dextrose solutions, usp (acd-a and acd-b) are approved products that are seldom used. **red blood cells (adenine saline added) are prepared by centrifuging whole blood to remove as much plasma as possible, and replacing the plasma with an additive solution that contains some combination of dextrose, adenine, sodium chloride, and either monobasic sodium phosphate (as-3) or mannitol (as-1 and as-5); the hematocrit is usually between 55 and 65%. Red cells in an additive solution have lower viscosity than red blood cells, and flow through administration systems in a manner more comparable to that of whole blood. Red cells stored with an additive solution have a shelf life of 42 days at 1-6 C. ***RBC cells leukocytes reduced: a unit of whole blood contains = or > 1-10 x 10 to the 9th white blood cells. Leukocyte-reduced blood is prepared by filtering blood with special filters that remove white blood cells by sieving and adherence mechanisms. Filtration may be done as follows: 1) soon after collection (pre-storage), 2) after varying periods of storage in the laboratory, or 3) at the bedside. The method used in the laboratory for leukocyte-reduction is subject to quality control testing; leukocyte-reduced components prepared at the bedside are not. Leukocyte reduction will decrease the cellular content and volume of blood according to characteristics of the filter system used. Whole blood, red blood cells, and platelets, pheresis leukocytes reduced must have a residual content of leukocytes <5 x 10 to the 6th. Platelets leukocytes reduced must have <8.3 x 10 to the 5th residual leukocytes. Leukocyte reduction filters variably remove other cellular elements in addition to white blood cells. Retention of 85% of the original therapeutic component is required. ****red blood cells frozen and red blood cells rejuvenated frozen are prepared by adding glycerol to red blood cells as a cryoprotective agent before freezing. The glycerol must be removed from the thawed component before it is infused. Frozen red cells may be stored for up to 10 years, and for longer intervals if there is particular need for specific units. *****red blood cells deglycerolized is the form in which cryo-preserved cells (red blood cells frozen) are available for infusion. Red blood cells deglycerolized contain 80% or more of the red cells in the original unit, and have approximately the same expected post transfusion survival as red blood cells. This product's use should be restricted to red cells with unusual antigenic phenotypes and for autologous donations when liquid-preserved blood cannot fulfill demands. This product may also be useful to patients with clinically significant immune reactivity against IgA. This product carries the risk of intravascular hemolysis if deglycerolization has been inadequate.
CyberLAB abbreviation: N/A
CyberLAB code: N/A
Lab Processing Instructions: Uncomplicated Routine - Completed within 8 hours of receipt. Uncomplicated Stat - Request for up to 4 units of blood must be completed with 60 minutes. Complicated Routine and Stat - Up to 6 units of blood require a minimum of 90-180 minutes or longer.