2014 Archived News Releases

Aspirin, Take Two
August 18, 2014
Hugely popular non-steroidal anti-inflammation drugs like aspirin, naproxen (marketed as Aleve) and ibuprofen (Advil, Motrin) all work by inhibiting or killing an enzyme called cyclooxygenase – a key catalyst in production of hormone-like lipid comp... (More)

Happiness in Schizophrenia
August 18, 2014
Schizophrenia is among the most severe forms of mental illness, yet some people with the disease are as happy as those in good physical and mental health according to a study led by researchers at the University of California, San Diego School of Me... (More)

New Mouse Model Points to Therapy for Liver Disease
August 18, 2014
Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and ... (More)

New Blood: Tracing the Beginnings of Hematopoietic Stem Cells
August 13, 2014
Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery. In a paper published online this week in Nature, researchers at the University of California... (More)

Prostate Cancer Diagnosis Improves with MRI Technology
August 12, 2014
Oncologists at UC San Diego Moores Cancer Center are the first in San Diego to meld magnetic resonance imaging (MRI) technology with a traditional ultrasound prostate exam to create a three-dimensional map of the prostate that allows physicians to v... (More)

Novel Study Maps Infant Brain Growth In First Three Months of Life Using MRI Technology
August 11, 2014
A recent study conducted by researchers at the University of California, San Diego School of Medicine and the University of Hawaii demonstrates a new approach to measuring early brain development of infants, resulting in more accurate whole brain gr... (More)

Clinical Trial Evaluates Safety of Stem Cell Transplantation in Spine
August 11, 2014
Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety of neural stem cell transplantation in patients with chronic spinal cord injuries. This Phase I clinical trial is recr... (More)

How Breast Cancer Usurps the Powers of Mammary Stem Cells
August 11, 2014
During pregnancy, certain hormones trigger specialized mammary stem cells to create milk-producing cells essential to lactation. Scientists at the University of California, San Diego School of Medicine and Moores Cancer Center have found that mammar... (More)

Target Identified For Rare Inherited Neurological Disease In Men
August 11, 2014
Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility. The study, pub... (More)

Dramatic Growth of Grafted Stem Cells in Rat Spinal Cord Injuries
August 07, 2014
Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran’s Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into... (More)

New Project to Reduce Heart Attacks and Strokes in San Diego County
August 04, 2014
Approximately 84 million people in the United States suffer from some form of cardiovascular disease, and about 720,000 Americans have a heart attack every year, which works out to one every 44 seconds. To address these alarming statistics, the Be T... (More)

Tumor Suppressor Mutations Alone Don’t Explain Deadly Cancer
August 04, 2014
Although mutations in a gene dubbed “the guardian of the genome” are widely recognized as being associated with more aggressive forms of cancer, researchers at the University of California, San Diego School of Medicine have found evidence suggesting... (More)

Pepper and Halt: Spicy Chemical May Inhibit Gut Tumors
August 01, 2014
Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin – the active ingredient in chili peppers – produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reactio... (More)

Birthday Matters for Wiring-Up the Brain’s Vision Centers
July 31, 2014
Researchers at the University of California, San Diego School of Medicine have evidence suggesting that neurons in the developing brains of mice are guided by a simple but elegant birth order rule that allows them to find and form their proper conne... (More)

Novel Technologies Advance Brain Surgery to Benefit Patients
July 24, 2014
In a milestone procedure, neurosurgeons at UC San Diego Health System have integrated advanced 3D imaging, computer simulation and next-generation surgical tools to perform a highly complex brain surgery through a small incision to remove deep-seate... (More)

UC San Diego Health System Among “Most Wired Advanced” in Nation
July 21, 2014
UC San Diego Health System is among the nation’s “Most Wired Advanced” hospitals, according to new findings released by Hospitals & Health Networks (H&HN), a publication of the American Hospital Association. The designation – given to just 2... (More)

Parents Rank Their Obese Children as “Very Healthy”
July 21, 2014
A University of California, San Diego School of Medicine-led study suggests that parents of obese children often do not recognize the potentially serious health consequences of childhood weight gain or the importance of daily physical activity in he... (More)

UC San Diego Health System Retains #1 Ranking
July 14, 2014
UC San Diego Health System remains among the nation’s best, according to the U.S. News & World Report’s 2014-15 issue of “America’s Best Hospitals,” released this week. The magazine’s widely cited findings again placed UC San Diego Health System... (More)

Acute Glaucoma Discovered to be an Inflammatory Disease
July 11, 2014
Researchers at the University of California, San Diego School of Medicine and Sun Yat-sen University in China have shown that acute glaucoma in mice is largely an inflammatory disease and that high pressure in the eye causes vision loss by setting i... (More)

Charles E. Daniels to be Honored for His Leadership in Health-System Pharmacy
July 09, 2014
The American Society of Health-System Pharmacists (ASHP) has named Charles E. Daniels, PhD, FASHP, as the recipient of the 2014 John W. Webb Lecture Award. The Webb Award honors health-system pharmacy practitioners or educators who stand apart becau... (More)

Minimally Invasive Heart Stents Prove Safer
July 09, 2014
Researchers at the University of California, San Diego School of Medicine have documented the safety benefits of aortic stent grafts inserted during minimally invasive surgery to repair abdominal aortic aneurysms – weaknesses in the body's largest a... (More)

New Approach to Remove Blood Clots
July 09, 2014
When a large blood clot was discovered attached to the end of a catheter inside the right atrial chamber of a patient’s heart, doctors faced a daunting challenge. If the clot came loose, the consequences would likely be catastrophic for the patient,... (More)

Rapid Surgical Innovation Puts Patients at Risk for Medical Errors
July 02, 2014
Researchers at the University of California, San Diego School of Medicine have found that the risk of patient harm increased two-fold in 2006 – the peak year that teaching hospitals nationwide embraced the pursuit of minimally invasive robotic surge... (More)

New Reprogramming Method Makes Better Stem Cells
July 02, 2014
A team of researchers from the University of California, San Diego School of Medicine, Oregon Health & Science University (OHSU) and Salk Institute for Biological Studies has shown for the first time that stem cells created using different metho... (More)

Upending a Cancer Dogma
July 02, 2014
Researchers at the University of California, San Diego School of Medicine say a protein essential to regulating cell cycle progression – the process of cell division and replication – activates a key tumor suppressor, rather than inactivating it as ... (More)

Biomarker Predicts Effectiveness of Brain Cancer Treatment
July 01, 2014
Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma – the most common form of primary brain cancer – will respond to chemotherapy. The findings are published in... (More)

McKerrow Appointed Dean of Skaggs School of Pharmacy and Pharmaceutical Sciences
June 30, 2014
Effective July 1, 2014, James H. McKerrow, MD, PhD, will become the second dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego. McKerrow will join UC San Diego from UC San Francisco, where he ... (More)

Marine Bacteria Are Natural Source of Chemical Fire Retardants
June 30, 2014
Researchers at the University of California, San Diego School of Medicine have discovered a widely distributed group of marine bacteria that produce compounds nearly identical to toxic man-made fire retardants. Among the chemicals produced by the o... (More)

Air Apparent: Using Bubbles to Reveal Fertility Problems
June 23, 2014
Many women struggling to become pregnant may suffer from some degree of tubal blockage. Traditionally, an x-ray hysterosalpingogram (HSG) that uses dye is the most common procedure to determine whether a blockage exists, but it can cause extreme dis... (More)

The Brain’s Balancing Act
June 23, 2014
Researchers at the University of California, San Diego School of Medicine have discovered a fundamental mechanism by which the brain maintains its internal balance. The mechanism, described in the June 22 advanced online publication of the journal N... (More)

UC San Diego Health System Designated U.S. Olympic Regional Medical Center
June 19, 2014
UC San Diego Health System has been designated an Official U.S. Olympic Regional Medical Center, joining a national network of leading medical providers selected by the United States Olympic Committee to provide comprehensive medical services to Tea... (More)

Finding the Achilles’ Heel of Ovarian Tumor Growth
June 19, 2014
A team of scientists, led by principal investigator David D. Schlaepfer, PhD, professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine report that small molecule inhibitors to a protein calle... (More)

Single Dose Reverses Autism-like Symptoms in Mice
June 17, 2014
In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleepi... (More)

Survey Finds E-Cigarette Online Market On Fire
June 17, 2014
Researchers at the University of California, San Diego School of Medicine have completed the first comprehensive survey of e-cigarettes for sale online and the results, they believe, underscore the complexity in regulating the rapidly growing market... (More)

Getting Rid of Old Mitochondria
June 16, 2014
It’s broadly assumed that cells degrade and recycle their own old or damaged organelles, but researchers at University of California, San Diego School of Medicine, The Johns Hopkins University School of Medicine and Kennedy Krieger Institute have di... (More)

How Our Brains Store Recent Memories, Cell by Single Cell
June 16, 2014
Confirming what neurocomputational theorists have long suspected, researchers at the Dignity Health Barrow Neurological Institute in Phoenix, Ariz. and University of California, San Diego School of Medicine report that the human brain locks down epi... (More)

Simulator Evaluates How Eye Diseases Affect Driving
June 13, 2014
The University of California, San Diego School of Medicine is the first ophthalmology department in the nation to feature a fully dedicated high-fidelity, highly realistic driving simulator for evaluating the effects of visual impairment on a person... (More)

Lower Vitamin D Level in Blood Linked to Higher Premature Death Rate
June 12, 2014
Researchers at the University of California, San Diego School of Medicine have found that persons with lower blood levels of vitamin D were twice as likely to die prematurely as people with higher blood levels of vitamin D. The finding, published ... (More)

A Key Step Toward a Safer Strep Vaccine
June 11, 2014
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, have identified the genes encoding a molecule that famously defines Group A Streptococcus (strep), a pathogenic bacterial species ... (More)

Herpes Infected Humans Before They Were Human
June 10, 2014
Researchers at the University of California, San Diego School of Medicine have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpa... (More)

HIV Transmission Networks Mapped to Reduce Infection Rate
June 05, 2014
Researchers at the University of California, San Diego School of Medicine have mapped the transmission network of human immunodeficiency virus (HIV) in San Diego. The mapping of HIV infections, which used genetic sequencing, allowed researchers to p... (More)

The Connection Between Oxygen and Diabetes
June 05, 2014
Researchers at the University of California, San Diego School of Medicine have, for the first time, described the sequence of early cellular responses to a high-fat diet, one that can result in obesity-induced insulin resistance and diabetes. The fi... (More)

Kelley Thompson honored with President’s Council Health Award
June 04, 2014
The President’s Council on Fitness, Sports & Nutrition (PCFSN) has selected Kelley Thompson to receive a 2014 PCFSN Community Leadership Award.  The award is given to individuals and organizations who significantly improve the lives of others th... (More)

How to Erase a Memory – And Restore It
June 02, 2014
Researchers at the University of California, San Diego School of Medicine have erased and reactivated memories in rats, profoundly altering the animals’ reaction to past events. The study, published in the June 1 advanced online issue of the journa... (More)

Melanoma of the Eye Caused by Two Gene Mutations
May 29, 2014
Researchers at the University of California, San Diego School of Medicine have identified a therapeutic target for treating the most common form of eye cancer in adults. They have also, in experiments with mice, been able to slow eye tumor growth wi... (More)

Gene Mutation Found for Aggressive Form of Pancreatic Cancer
May 27, 2014
Researchers at the University of California, San Diego School of Medicine have identified a mutated gene common to adenosquamous carcinoma (ASC) tumors – the first known unique molecular signature for this rare, but particularly virulent, form of pa... (More)

Cancer Avatars for Personalized Medicine
May 21, 2014
Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have used computer simulations of cancer cells – cancer avatars – to identify drugs most likely to kill cancer cells isolated from patients’ brain tumors.... (More)

Possible Cause and Source of Kawasaki Disease Found
May 19, 2014
An international team of scientists, including researchers from the University of California, San Diego, report that the likely causative agent of Kawasaki disease (KD) in Japan is a windborne agent originating from a source in northeast China. KD i... (More)

Solution to Helping Teens with Chronic Disease May be at Fingertips
May 19, 2014
Adolescents with chronic diseases (ACD), such as cystic fibrosis, gastrointestinal disorders (including Crohn’s disease) and Type 1 diabetes, often find the transition of managing their health care needs into adulthood to be challenging. Preparation... (More)

War and Peace (of Mind)
May 16, 2014
Researchers from the University of California, San Diego School of Medicine and Naval Health Research Center have found that mindfulness training – a combination of meditation and body awareness exercises – can help U.S. Marine Corps personnel prepa... (More)

Weather Safety Tips from UC San Diego Experts
May 16, 2014
A heat advisory is still in effect in San Diego County with temperatures rising to more than 100 degrees in some areas. During this extreme weather, with the possibility of significant smoke pollution, UC San Diego Health System experts offer tips f... (More)

E-Cigarettes and Mental Health
May 13, 2014
Researchers at University of California, San Diego School of Medicine report that people living with depression, anxiety or other mental health conditions are twice as likely to have tried e-cigarettes and three times as likely to be current users o... (More)

Detecting Fetal Chromosomal Defects Without Risk
May 06, 2014
Chromosomal abnormalities that result in birth defects and genetic disorders like Down syndrome remain a significant health burden in the United States and throughout the world, with some current prenatal screening procedures invasive and a potentia... (More)

Genetic Risk Factor for Premature Birth Found
May 05, 2014
Researchers at the University of California, San Diego School of Medicine have discovered a genetic risk factor for premature birth. The risk factor is related to a gene that codes for a protein that the scientists have found helps the body’s immune... (More)

Molecular Tumor Board Helps in Advanced Cancer Cases
May 05, 2014
With accelerating development of personalized cancer treatments matched to a patient’s DNA sequencing, proponents say frontline physicians increasingly need help to maneuver through the complex genomic landscape to find the most effective, individua... (More)

UC San Diego Launches New Center on Healthy Aging and Senior Care
May 02, 2014
Dilip V. Jeste, MD, Distinguished Professor of Psychiatry and Neurosciences, has been appointed the first associate dean for Healthy Aging and Senior Care at the University of California, San Diego and will direct the newly established Center on Hea... (More)

Damage Control: Recovering From Radiation and Chemotherapy
April 30, 2014
Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation expos... (More)

MRI-Guided Biopsy for Brain Cancer Improves Diagnosis, California First
April 30, 2014
Neurosurgeons at UC San Diego Heath System have, for the first time, combined real-time magnetic resonance imaging (MRI) technology with novel non-invasive cellular mapping techniques to develop a new biopsy approach that increases the accuracy of d... (More)

Prostate Cancer and Blood Lipids Share Genetic Links
April 30, 2014
Numerous studies have suggested a relationship between cardiovascular disease risk factors and prostate cancer. A new study by researchers at the University of California, San Diego School of Medicine, with colleagues in Norway, significantly refine... (More)

UC San Diego Health System Excels in Patient Safety
April 29, 2014
Designed to rate how well hospitals protect patients from accidents, errors, injuries and infections, the latest Hospital Safety Score honored UC San Diego Health System with an “A” – its top grade in patient safety. The Hospital Safety Score is com... (More)

Researchers Discover New Genetic Brain Disorder in Humans
April 24, 2014
A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell. The findings were generated by two independent ... (More)

Community-Based Weight Loss Program Aids Diabetes Management
April 23, 2014
Weight loss and control of blood sugar can reduce the risk of complications in patients with diabetes but this is difficult for many to achieve. A University of California, San Diego School of Medicine randomized controlled trial of obese adults wit... (More)

Igor Grant Named Chair of UC San Diego Department of Psychiatry
April 22, 2014
Igor Grant, MD, FRCP(C), an internationally recognized neuropsychiatrist, whose research interests have ranged from the neurobiology of HIV/AIDS and substance abuse, psychobiology of stress, to the therapeutic potential of medicinal cannabis, has be... (More)

Cancer Stem Cells Linked to Drug Resistance
April 21, 2014
Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD... (More)

The Ilk of Human Kindness
April 17, 2014
Researchers at the University of California, San Diego School of Medicine report that older women, plucky individuals and those who have suffered a recent major loss are more likely to be compassionate toward strangers than other older adults. The ... (More)

Mutant Protein in Muscle Linked to Neuromuscular Disorder
April 16, 2014
Sometimes known as Kennedy’s disease, spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. Researchers have long considered it to be essentially an affl... (More)

Breaking Bad Mitochondria
April 15, 2014
Researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long. The hard-to-k... (More)

Splice Variants Reveal Connections Among Autism Genes
April 10, 2014
A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology (CCSB) at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in auti... (More)

For Good and Ill, Immune Response to Cancer Cuts Both Ways
April 07, 2014
The difference between an immune response that kills cancer cells and one that conversely stimulates tumor growth can be as narrow as a “double-edged sword,” report researchers at the University of California, San Diego School of Medicine in the Apr... (More)

Cancer and the Goldilocks Effect
April 03, 2014
Researchers at the University of California, San Diego School of Medicine have found that too little or too much of an enzyme called SRPK1 promotes cancer by disrupting a regulatory event critical for many fundamental cellular processes, including p... (More)

UC San Diego Medical Center Named Among 100 Great Hospitals in U.S.
April 02, 2014
The University of California, San Diego Medical Center in Hillcrest has been named one of  “100 Great Hospitals in America” by Becker’s Hospital Review, a publishing group that conducts hospital and healthcare news and analyses, which described the ... (More)

Good Vibrations: Using Light-Heated Water to Deliver Drugs
April 01, 2014
Researchers from the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, in collaboration with materials scientists, engineers and neurobiologists, have discovered a new mechanism for using light to activate dr... (More)

Gulf War Illness Not in Veterans’ Heads, But in Their Mitochondria
March 27, 2014
Researchers at the UC San Diego School of Medicine have demonstrated for the first time that veterans of the 1990-91 Persian Gulf War who suffer from “Gulf War illness” have impaired function of mitochondria – the energy powerhouses of cells. The ... (More)

Patches of Cortical Layers Disrupted During Early Brain Development in Autism
March 26, 2014
Researchers at the University of California, San Diego School of Medicine and the Allen Institute for Brain Science have published a study that gives clear and direct new evidence that autism begins during pregnancy. The study will be published in... (More)

Ferrara Receives Gairdner Prize, Canada’s Highest Honor in Life Sciences
March 26, 2014
Napoleone Ferrara, MD, distinguished professor of pathology at the University of California, San Diego School of Medicine and senior deputy director for basic sciences at UC San Diego Moores Cancer Center, was named today among eight recipients of t... (More)

Brain Differences in College-aged Occasional Drug Users
March 25, 2014
Researchers at the University of California, San Diego School of Medicine have discovered impaired neuronal activity in the parts of the brain associated with anticipatory functioning among occasional 18- to 24-year-old users of stimulant drugs, suc... (More)

Stem Cell-Derived Beta Cells Under Skin Replace Insulin
March 25, 2014
Scientists at University of California, San Diego School of Medicine and Sanford-Burnham Medical Research Institute have shown that by encapsulating immature pancreatic cells derived from human embryonic stem cells (hESC), and implanting them under ... (More)

Bariatric Surgery Decreases Risk of Uterine Cancer
March 24, 2014
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center report that bariatric surgery resulting in dramatic weight loss in formerly severely obese women reduces the risk of endometrial (uterine) cancer by 7... (More)

New Therapeutic Target Discovered for Alzheimer’s Disease
March 17, 2014
A team of scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and San Diego-based American Life Science Pharmaceuticals, Inc., report that cathepsin B gene knockout or its reduction by... (More)

Mother Delivers Baby, Develops Heart Disease
March 11, 2014
Three weeks after delivering her first child, Amanda began to suffer from extreme fatigue, headaches, a tight chest and stomach pain. An initial diagnosis of pneumonia changed for the worse: Amanda was experiencing heart failure. The 28-year-old’s l... (More)

Anti-psychotic Medications Offer New Hope in the Battle Against Glioblastoma
March 07, 2014
Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was p... (More)

Kawasaki Disease and Pregnant Women
March 06, 2014
In the first study of its type, researchers at the University of California, San Diego School of Medicine have looked at the health threat to pregnant women with a history of Kawasaki disease (KD), concluding that the risks are low with informed man... (More)

Vitamin D Increases Breast Cancer Patient Survival
March 06, 2014
Breast cancer patients with high levels of vitamin D in their blood are twice as likely to survive the disease as women with low levels of this nutrient, report University of California, San Diego School of Medicine researchers in the March issue of... (More)

UC San Diego-Human Longevity Inc. Agreement Seeks to Accelerate Medical Science
March 04, 2014
The new collaborative research agreement between Human Longevity Inc. (HLI) and the University of California, San Diego, announced today, represents a significant and necessary step in efforts to research and translate the potential of the human gen... (More)

In First Moments of Infection, a Division and a Decision
March 04, 2014
Using technologies and computational modeling that trace the destiny of single cells, researchers at the University of California, San Diego School of Medicine describe for the first time the earliest stages of fate determination among white blood c... (More)

California’s First MRI-Guided Laser Treatment for Brain Cancer
February 24, 2014
Using a novel magnetic resonance imaging (MRI)-guided laser technology, neurosurgeons at UC San Diego Health System have successfully treated a malignant tumor deep inside a patient’s brain. This is the first time that this FDA-approved laser-based ... (More)

Study Evaluates Role of Infliximab in Treating Kawasaki Disease
February 24, 2014
Kawasaki Disease (KD) is a severe childhood disease that many parents, even some doctors, mistake for an inconsequential viral infection. If not diagnosed or treated in time, it can lead to irreversible heart damage. Signs of KD include prolonged ... (More)

Improving Knee Replacements
February 18, 2014
Each year, approximately 600,000 total knee replacement procedures are performed in the United States, a number that is expected to rise exponentially in the next decade as the population ages. Successful surgeries require precise alignment in the k... (More)

Child obesity: Cues and Don’ts
February 14, 2014
Among the multiple factors that can cause obesity is an abnormal neurocognitive or behavioral response to food cues. The brain becomes wired to seek – and expect – greater rewards from food, which leads to unhealthful overeating. Attention modifica... (More)

Protein Switch Dictates Cellular Fate: Stem Cell or Neuron
February 13, 2014
Researchers at the University of California, San Diego School of Medicine have discovered that a well-known protein has a new function: It acts in a biological circuit to determine whether an immature neural cell remains in a stem-like state or proc... (More)

I Smoke, But I’m Not a Smoker
February 11, 2014
While smoking among California adults has dramatically declined in recent decades, researchers at the University of California, San Diego School of Medicine report there is a surprisingly large number of people who say they use cigarettes, but don’t... (More)

Global Regulator of mRNA Editing Found
February 06, 2014
An international team of researchers, led by scientists from the University of California, San Diego School of Medicine and Indiana University, have identified a protein that broadly regulates how genetic information transcribed from DNA to messenge... (More)

Split Decision: Stem Cell Signal Linked With Cancer Growth
February 03, 2014
Researchers at the University of California, San Diego School of Medicine have identified a protein critical to hematopoietic stem cell function and blood formation. The finding has potential as a new target for treating leukemia because cancer stem... (More)

CIRM Awards $8.165 Million in Basic Biology Awards to UC San Diego
January 30, 2014
Eight stem cell scientists at the University of California, San Diego have been awarded a total of $8.165 million to fund research tackling significant, unresolved issues in human stem cell biology. The California Institute for Regenerative Medici... (More)

Scientists Discover New Genetic Forms of Neurodegeneration
January 30, 2014
In a study published in the January 31, 2014 issue of Science, an international team led by scientists at the University of California, San Diego School of Medicine report doubling the number of known causes for the neurodegenerative disorder known ... (More)

How DNA Damage Affects Golgi – The Cell’s Shipping Department
January 30, 2014
In studying the impact of DNA damage on the Golgi, a research team from the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered a novel pathway activated by DNA damage, with important c... (More)

UC San Diego Health System Top Ranked by Healthgrades
January 29, 2014
UC San Diego Health System is a recipient of Healthgrades’ “Distinguished Hospital Award for Clinical Excellence.” Top performing hospitals were selected based on clinical excellence across a broad spectrum of care in specialty areas such as cardiac... (More)

H.M.'s Brain Yields New Evidence
January 28, 2014
3D model of famous amnesiac's brain helps illuminate human memory During his lifetime, Henry G. Molaison (H.M.) was the best-known and possibly the most-studied patient of modern neuroscience.  Now, thanks to the postmortem study of his brain, bas... (More)

Putting a Brake on Tumor Spread
January 23, 2014
A team of scientists, led by principal investigator David D. Schlaepfer, PhD, a professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine, has found that a protein involved in promoting tumor ... (More)

Drug Discovery Potential of Natural Microbial Genomes
January 22, 2014
Advanced genetic technique yields novel antibiotic from ocean bacteria Scientists at the University of California, San Diego have developed a new genetic platform that allows efficient production of naturally occurring molecules, and have used it t... (More)

Nationwide Minimally Invasive Surgery Rates Triple for Pancreatic Disease
January 15, 2014
Researchers at University of California, San Diego School of Medicine report a three-fold increase in the use of minimally invasive surgery (MIS) across the nation for patients with pancreatic disease.  Although adaptation of MIS for this difficult-... (More)

UC San Diego Health System Among Nation’s Best in Women’s Health
January 15, 2014
Named to Becker’s Hospital Review’s “100 Hospitals with Great Women’s Health Programs”  UC San Diego Health System has been featured in the latest Becker’s Hospital Review list of “100 Hospitals with Great Women’s Health Programs.” Hospitals were ... (More)

Keeping Stem Cells Pluripotent
January 13, 2014
By blocking key signal, researchers maintain embryonic stem cells in vital, undifferentiated state While the ability of human embryonic stem cells (hESCs) to become any type of mature cell, from neuron to heart to skin and bone, is indisputably cru... (More)

Study Demonstrates Need to Change Scoring System for Heart Disease
January 13, 2014
Dense Heart Plaques May Have Protective Quality A study led by researchers at the University of California, San Diego School of Medicine shows that one of the most widely used systems for predicting risk of adverse heart events should be re-evaluat... (More)

Football Fans Team Up for Organ Match
January 08, 2014
Random stadium seat assignment leads to lifesaving transplant surgery In October 2013, Louis Munoz donated one of his kidneys to William Lynch. The organ match would not have occurred without a bit of serendipity and a big love of football. Munoz a... (More)

Treating the inner animal in all of us
January 08, 2014
New veterinary and comparative medicine center advances health care, human and otherwise Discoveries about how diseases arise or are transmitted in animals can be useful in understanding the same sorts of afflictions in humans. Similarly, new ther... (More)

Conference Attracts International Experts in Field of Mindfulness and Child Development to San Diego
January 07, 2014
Featured Speakers include Daniel Siegel, Sharon Salzberg and Congressman Tim Ryan Experts in the field of mindfulness will gather in San Diego from Feb. 7-9 to share the latest advancements in education, clinical care and research as it applies to ... (More)

The Mouse That ROR’ed
January 02, 2014
ROR1 oncogene combines with another to accelerate, worsen blood cancer Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal... (More)