LMWH Therapeutic Range and Monitoring - Anticoagulation Clinic - UC San Diego Health System

Anticoagulation Clinic

Therapeutic Range and Monitoring

Enoxaparin does not affect PTT or INR

Anti-factor Xa

  • Levels can be measured and are generally used to monitor enoxaparin activity in certain subgroups of patients.
  • Anti-Xa levels may be recommended in underweight, obese, pregnant, or renally impaired patients.
  • Anti-Xa levels should be checked at their peak at 4 hours after dosing (both q12 and q24 variations).
  • Reference ranges are not clinically validated and can vary by facility and indication for use.
  • Suggested "therapeutic range" is usually 0.6-1.0 units/mL.