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Warfarin is a very individualized medication without a “standard” dose. In order to optimize the therapeutic effect and minimize complications such as bleeding, close monitoring of the degree of anticoagulation is required. During the initial stage of therapy, expect to check the INR frequently. The intervals between tests can be lengthened if the patient maintains stable target-range INR levels on an unchanged warfarin dose.
Check baseline labs:
Consider beginning with lower initial doses for:
After a dosing regimen is established, it is advisable to consolidate to a single strength of warfarin. While not problematic in select patients, use of multiple tablet strengths can lead to confusion, medication errors and adverse events.
UC San Diego Inpatient Warfarin Initiation found through Web Ref provides a detailed daily guide to warfarin dosing.
Official Web Site of the University of California, San Diego.