ALS Clinical Trials

Welcome to the ALS Clinical Trials (ACT) Program.

Led by John Ravits, MD, our team is dedicated to clinical research in the field of amyotrophic lateral sclerosis (ALS).



ALS Patient Interview

You do not need to be a patient of the ALS Clinic to participate in clinical research at UC San Diego.

(Status: no longer recruiting)
The study drug, tirasemtiv is being investigated as a potential new therapy for the improvement of muscle weakness and muscle fatigue in patients with ALS. The purpose of this research study is to evaluate the safety and effectiveness of tirasemtiv and how well it is tolerated in patients with ALS. The length of the study, including screening, dosing and follow up, is approximately 20 weeks.

Pre-fALS Study

ALS patient gets their blood pressure taken

When participating in clinical trials, ALS patients receive regular medical checkups.

(UC San Diego is in the process of becoming a study site and more information will be posted soon)
This is a longitudinal observational study of people who are at risk for developing familial ALS (fALS), with the specific goal of improving our understanding of the pre-symptomatic phase of fALS. The investigators at the University of Miami are actively recruiting unaffected relatives of people with fALS to participate in the study. If you are interested in participating or want more information please visit and search for "fALS" in the "Search for Studies" search bar.

Contact ALS Clinical Trials

Aaryn Belfer

Aaryn Belfer is a senior clinical research coordinator for the ALS Clinical Trials (ACT) Program UC San Diego. Aaryn has extensive experience in all aspects of Phase II-IV clinical trials and possesses in-depth knowledge of clinical research methodology. She serves as a liaison between UC San Diego and various sponsors and their partners, CROs and the UC San Diego Human Research Protection Program; she ensures that research-related activities are performed in accordance with all regulatory policies and procedures. Her favorite part of her job is interacting and building relationships with participants. Her favorite part of her non-working hours is spending time goofing around with her husband and daughter. In her spare time, she is a freelance writer, hobbyist photographer, globe trotter and practitioner of yoga.