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by Philip O. Anderson, PharmD, FASHP, FCSHP
Director, Drug Information Service, University of California San Diego Medical Center
Clinical Professor of Pharmacy, University of California San Diego & University of California San Francisco
These drugs should be avoided during lactation if possible. If they are essential to the mother's health, breastfeeding may have to be discontinued temporarily or permanently.
Although not absolutely contraindicated, an alternative drug in the same class should be used from one of the lists below, particularly while breastfeeding an infant of 2 months of age or less.
There are insufficient data to absolutely ensure that these agents have no adverse effects in breastfeeding infants, but if they occur they are probably infrequent and/or mild. The potential for rare allergic or idiosyncratic reactions should be kept in mind.
Although the potential for rare allergic or idiosyncratic reactions should be kept in mind, usual doses pose little risk for the breastfed infant.
*Drug may also inhibit lactation.
**In situations where bottle feeding poses a grave threat to the infant's life, breastfeeding may be undertaken cautiously.
Sources: (1) Anderson PO et al., eds.(2002) Handbook of Clinical Drug Data, 10th ed. McGraw-Hill; (2) Anderson PO (1991) Drug use during breast-feeding Clin Pharm 10:596-624. (3) UCSD Drug Information Service 619-543-6971. For health professionals and nursing mothers.
Note: The information contained in this document is time-limited. It is current and accurate as of 4/05
Official Web Site of the University of California, San Diego.