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Trauma Research and Clinical Trials

Clinical Research Study on Severe Brain Trauma

UC San Diego Health is part of a national research study that will see if oxygen under pressure can help people ages 16 to 65 with severe traumatic brain injury. This treatment is also known as hyperbaric oxygen therapy, which involves inhaling 100 percent oxygen in a hyperbaric oxygen chamber equivalent to the size of a small school bus. Our Hyperbaric Medicine and Wound Care program is among the largest and most sophisticated in California.

The goal of the national trial, called Hyperbaric Oxygen Brain Injury Treatment (HOBIT), is to identify the best way to deliver hyperbaric oxygen therapy so that patients with severe brain injuries can recover with less disability. Because the experimental treatment must be given quickly, patients may be enrolled in the trial without informed consent. All patients will receive standard care for their traumatic brain injury. For more information, visit the HOBIT trial website or to learn how to opt out, contact the research team at 619-543-7218.

Learn About Trauma Research

Our faculty in the Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery is dedicated to improving health outcomes for critically injured patients and those in acute surgical need.

Our success is due in large part to our collaborative energy and partnerships — bringing together experts in academic medicine, basic scientists, epidemiologists, public health professionals, emergency medical professionals, city and county government officials, and most importantly, the public.

UC San Diego Health clinical and research faculty members are engaged in a robust research program that includes clinical outcomes and basic science / translational research. Our multidisciplinary approach is supported by collaboration with colleagues from several departments across the UC San Diego School of Medicine.

Clinical Research

Our clinical research efforts use both institutional databases and large-scale data sources to ask clinically relevant questions to improve the care of our patients. Our faculty actively participate in, and often lead multicenter studies aimed at addressing clinical topics that have helped shape the management of trauma and critical care internationally.

Basic Science Research

Our NIH-funded basic-science research group consists of an integrated team of surgeon-scientists and PhD researchers who share a common goal of performing "bench to bedside" research. We use cellular, molecular, and genetic techniques to better understand the human injury response with the goal of improving outcomes in patients following severe injury and infection.

Contact Us

  • Trauma Center: 619-543-6222
  • Clinical care appointments and referrals: 619-543-6886
  • Administrative offices (not for new patients or referrals): 619-543-7200
  • For Referring Physicians

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UC San Diego – Hillcrest

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