Kidney Stone Research

UC San Diego Health conducts numerous studies specific to kidney stones. Talk to your urologist to learn more about these studies and if you are a candidate for them. Go to research and clinical trials for more information on developments in urologic health.

Ureteral Stent Research
We are attempting to design a novel ureteral stent that will minimize discomfort. Currently, ureteral stents are a source of pain for kidney stone patients who undergo surgery. Although the redesigned stent is not currently available for clinical use, we are actively researching this important area.

The Role of Tamm Horsfall Protein (THP) in Kidney Stone Formation
UC San Diego Health is currently collecting urine to determine if specific proteins found in urine (THP) are abnormal in their levels as well as in their configuration. THP is an abundant urinary protein in mammals that potentially has a protective role in kidney stone formation. We hypothesize that THP levels are lower in kidney stone formers and therefore this places them at higher risk of kidney stone formation. Time and risk are minimal for this study.

Double Blinded, Placebo Controlled Study of Silodison to Facilitate Urinary Stone Passage
Dr. Sur is the Principal Investigator of a multi-institutional study evaluating the efficacy of the alpha-blocker medication, silodison (Rapaflo), in expediting the spontaneous passage of kidney stones. Our goal is to obtain 240 subjects nationwide.

Use of Acupuncture to Decrease Kidney Stone Surgery Pain and Minimize Pre-op Anxiety
UC San Diego Health is currently examining the use of traditional acupuncture to minimize narcotic requirements after surgery. The acupuncture is also used pre-operatively to decrease patient anxiety.

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