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Peyronie's Disease

Peyronie's disease is a disorder where scar tissue (plaque) builds up inside the penis. As the plaque forms, the penis will bend or curve, which can result in painful erections and make sexual intercourse difficult, painful or impossible. The first sign of Peyronie's disease is inflammation.

While the cause of Peyronie's disease is often unknown, factors that may increase your risk include:

  • Chronic injury to the penis, such as microscopic damage as a result of forceful sexual or nonsexual activities
  • Acute injury to the penis
  • Autoimmune disorders, such as systemic lupus erythematosus
  • Connective tissue disorders, such as plantar fasciitis
  • Aging
  • Family history of Peyronie's disease

Symptoms of Peyronie's disease can be mild to severe, and develop slowly or quickly. The pain often lessens over time, however the curve may remain. Surgery has shown to be the most effective treatment for severe cases of Peyronie's disease.

Surgical Treatment for Peyronie's Disease

Peyronie's disease often resolves on its own. Surgery may be recommended to remove plaque if curvature has been present for longer than 12 months and:

  • Symptoms are not improving on their own
  • The disease is not responding to nonsurgical therapy
  • Erections or intercourse is painful
  • The penis is so curved that intercourse is impossible

Our team has expertise in surgical therapies that decrease pain and reinstate the ability to have intercourse, including:

  • Plication: This procedure helps straighten the penis by removing or pinching the tunica albuginea opposite the plaque. This procedure may cause erectile dysfunction, numbness, or shortening of penis.
  • Device implantation: A device that helps straighten the penis during erection is implanted into the penis. This procedure may be considered if both Peyronie's disease and erectile dysfunction is present. This may be combined with plication or grafting if the implant alone does not straighten the penis.
  • Grafting: The plaque is removed and replaced with a vein, patch of skin, or material made from animal organs. This procedure can restore lost length and may reduce curvature; however, a side effect is numbness and erectile dysfunction.

Appointments and Referrals


La Jolla