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UFH and LMWH Dose

UFH (Unfractionated heparin - no prefilled syringes)

  • Most common concentration is 10,000units/mL, comes in 5mL vial
  • Don’t forget to prescribe syringes
  • Therapeutic UFH = 8000-10,000 IU SC every 8 hours, or 15,000-20,000 IU SC every 12 hours.
  • Prophylactic UFH = 5000 IU SC every 8-12 hours, or 7500 units SC every 12 hours

LMWH (Low molecular weight heparin)

  • Round to nearest prefilled syringe (i.e. don’t prescribe 90mg of Lovenox)
  • Last dose 24 hours prior to procedure
  • Resume 24 hours (or more) post procedure based on adequate hemostasis
  • Enoxaparin (Lovenox): Comes in prefilled syringes 30mg, 40mg, 60mg, 80mg, 100mg, 120mg, 150mg
    • Therapeutic Lovenox = 1.5mg/kg/day or 1mg/kg/bid
    • Prophylactic Lovenox = 30-40mg/day
  • Dalteparin (Fragmin): Comes in prefilled syringes 2500units, 5000units, 7500units, 10,000units, 12,500units, 15,000units, 18,000units, 25,000units
    • Therapeutic Fragmin = 200units/kg/day
    • Prophylactic Fragmin = 2500-5000units/day