COVID-19 updates, including vaccine information, for our patients and visitors Learn More

Menu
Search

UCSD Researchers Identify Connection between Sleep Disruption and Increased Cardiovascular Risk In Healthy Men and Women

 

March 29, 2007  |  

Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that sleep disruption in seemingly healthy subjects is associated with increased clotting of the blood, which has previously been shown to predict cardiovascular disease. The findings were published in the March issue of CHEST, the official publication of the American College of Chest Physicians.

“In previous work, we have found that sleep disruption was linked to pro-coagulant (i.e, pro-clotting) activity in patients with sleep apnea, and in patients facing harrowing long-term stress. Now, we have seen the same pattern of findings even in healthy normal subjects,” said Joel E. Dimsdale, M.D., Professor of Psychiatry at UCSD.

Full-night polysomnography, a sleep study that involves recording brain waves and airflow at the nose and mouth, was performed in 135 men and women, average age 36, who had no history of sleep disorders. Through these measurements, a parallel correlation was found between higher levels of spontaneous sleep disruption and higher levels of compounds in the blood that serve as markers for clotting.

“Sleep disruption needs to be taken seriously,” said Dimsdale. “It is known that certain forms of sleep disruption such as obstructive sleep apnea convey extensive cardiovascular risk. We now know that sleep disruption is a potential factor in heart disease even in the average person.”

Additional contributors to this study include Paul J. Mills, Ph.D., and Sonia Ancoli-Israel, Ph.D., from the Department of Psychiatry; Jose S. Loredo, M.D., Department of Medicine; and Loki Natarajan, Ph.D., Department of Family and Preventive Medicine at University of California San Diego, La Jolla, CA, and Roland von Känel, M.D., Department of General Internal Medicine, from University Hospital Berne, Switzerland. The research was funded by a grant from the National Institutes of Health.

# # #

Media Contact:  Jackie Carr, 619-543-6163, jcarr@ucsd.edu

 

 

 




Media Contact

Share This Article


Related News

10/14/2021
The National Institutes of Health (NIH) has awarded researchers at University of California San Diego approximately $30 million over five years to expand and deepen longitudinal studies of the develop ...
10/13/2021
UC San Diego Health announces it has been recognized as a top performer in the 2021 Bernard A. Birnbaum, MD, Quality Leadership Annual Ranking by Vizient Inc.
10/13/2021
UC San Diego researchers report that conducting genomic evaluations of advanced malignancies can be effective in guiding first-line-of-treatment, rather than waiting until standard-of-care therapies h ...
10/12/2021
Jacobs Medical Center at UC San Diego Health marks its fifth anniversary and celebrates achievements and milestones while providing the most advanced medical and surgical care in the region.



Follow Us