Translate
Translate this website into the following languages:



Close Tab
Donations
UC San Diego Health
menu iconMenu
search iconSearch

Karl Y. Hostetler, MD, Receives Prestigious 2012 Gertrude Elion Memorial Award

 

April 17, 2012  |  

Karl Y. Hostetler, MD, has been selected as the recipient of the 2012 Gertrude Elion Memorial Lecture Award by the International Society of Antiviral Research.  Hostetler is a professor of medicine in the Divisions of Infectious Diseases and Endocrinology at the UC San Diego School of Medicine. Each year the award is given to a scientist of international repute who has made significant contributions to the field of antiviral research and to mentoring of young scientists. The award will be presented during the International Conference on Antiviral Research in Sapporo, Japan on April 16. 

 

Hostetler
Karl Hostetler, MD, UC San Diego School of Medicine
“I had the privilege of meeting Dr. Elion at Burroughs Wellcome early in my career while developing an alternate version of AZT,” said Hostetler. “I am deeply gratified to receive the 2012 Gertrude Elion Memorial Award on behalf of myself, my coworkers and the UC San Diego School of Medicine.”

 

Hostetler is an international expert in the design, synthesis and evaluation of novel orally active antivirals for poxviruses such as smallpox, monkeypox, cowpox, and ectromelia as well as for cytomegalovirus, herpes simplex, and other double stranded DNA viruses.   He has also advanced the discovery and development of high potency antiretrovirals for drug-resistant HIV. 

He is a founder of three biotech companies, Vical Inc., Triangle Pharmaceuticals, and Chimerix Inc., which are dedicated to developing lifesaving drugs in the treatment of serious viral infections and cancer.  Hostetler holds 43 U.S. patents and has published more than 160 peer-reviewed scientific articles.

Hostetler’s lecture will recount the discovery of novel antiviral agents using a patented lipid conjugation technique to create AIDS drugs which are more potent, active against a broad range of drug resistant HIV variants, and require infrequent dosing. 

“Dr. Elion discovered acyclovir, the first commercially successful antiviral, for which she received the Nobel Prize in 1988.  The development of this drug was followed by a large number of new antiviral agents which have profoundly improved the treatment of AIDS, hepatitis B and C,” said Hostetler.  

Hostetler received his undergraduate degree in chemistry from DePauw University in Greencastle, Indiana in 1961 and his medical degree from the Western Reserve University School of Medicine in Cleveland, Ohio in 1965. He completed his internship and residency in internal medicine at University Hospitals of Cleveland and a fellowship in endocrinology and metabolism at the Cleveland Clinic Foundation. He currently serves as Director of the Endocrinology Clinic at the San Diego VA Medical Center and is an associate member of the UC San Diego Moores Cancer Center.

# # #

Media Contact: Jackie Carr, 619-543-6163, jcarr@ucsd.edu


Related Specialties



Media Contact

Share This Article


Related News

2/22/2017
University of California San Diego School of Medicine researchers screened 10,000 colonies of bacteria found on the epidermis to determine how many had antimicrobial properties and at what rate these ...
2/17/2017
An international research team, led by principal investigator Elizabeth A. Winzeler, PhD, professor in the pediatric division of host-microbe systems and therapeutics at University of California San D ...
2/16/2017
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial scourge that is resistant to most common antibiotics and thus difficult to treat, particularly in children where it commonly causes co ...
2/15/2017
A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has developed a new tool to analyze an often overlooked aspect of cancer genetics — an alteratio ...



Follow Us

Our bimonthly newsletter delivers healthy lifestyle tips, patient stories and research discovery news. Subscribe: