All of Us Research Program officially opens for enrollment Sunday, May 6. Led by the National Institutes of Health (NIH),
All of Us is an unprecedented effort to gather genetic, biological, environmental, health and lifestyle data from 1 million or more volunteer participants living in the United States. A major component of the federal Precision Medicine Initiative, the program’s ultimate goal is to accelerate research and improve health.
Unlike research studies that are focused on a specific disease or population,
All of Us will serve as a national research resource to inform thousands of studies, covering a wide variety of health conditions. Researchers will be able to access data from the program to learn more about how individual differences in lifestyle, environment and biological makeup can influence health and disease. Participants will be able to access their own health information, summary data about the entire participant community and information about studies and findings that come from
All of Us.
Lucila Ohno-Machado, MD, PhD, leads the All of Us Research Program at UC San Diego Health.
In California, the
All of Us Research Program is being implemented by the California Precision Medicine Consortium, which is co-led by Lucila Ohno-Machado, MD, PhD, at UC San Diego Health and Hoda Anton-Culver, PhD, at UCI Health. The consortium also includes UC Davis, UC San Francisco, Keck School of Medicine of the University of Southern California, Cedars-Sinai Medical Center and the San Diego Blood Bank. In San Diego, San Ysidro Health is also enrolling participants, and the Scripps Translational Science Institute at The Scripps Research Institute is working with corporate partners to enroll participants nationwide.
“We hope Californians from all backgrounds will want to participate in
All of Us to help make history and change the future of health,” said Ohno-Machado, professor and chair of the Department of Biomedical Informatics at UC San Diego Health and associate dean for informatics and technology at UC San Diego School of Medicine. “We look forward to sharing this exciting journey with our many participants.”
Congress has authorized $1.455 billion over 10 years for
All of Us. More than 25,000 people nationwide have already joined the program as part of a yearlong beta testing phase that helped shape the participant experience.
“The time is now to transform how we conduct research — with participants as partners — to shed new light on how to stay healthy and manage disease in more personalized ways. This is what we can accomplish through
All of Us,” said NIH Director Francis S. Collins, MD, PhD.
How to Participate
Photo courtesy of the National Institutes of Health
- To learn more about the
All of Us Research Program and how to join, please visit
- Participants are asked to share different types of health and lifestyle information, including through online surveys and electronic health records, which will continue to be collected over the course of the program.
- At different times over the coming months and years, some participants will be asked to visit a local partner site to provide blood and urine samples and to have basic physical measurements taken, such as height and weight. In San Diego, that may take place at UC San Diego Health, San Ysidro Health or a San Diego Blood Bank location.
To ensure that the program gathers information from all types of people, especially those who have been underrepresented in research, not everyone will be asked to give physical measures and samples. In the future, participants may be invited to share data through wearable devices and to join follow-up research studies, including clinical trials. Also in future phases of the program, children will be able to enroll, and the program will add more data types, such as genetic data.
Data from the program will be broadly accessible for research purposes. Ultimately, the
All of Us Research program will be a rich and open data resource for traditional academic researchers as well as citizen scientists — and everyone in between.
“All of Us” is a registered service mark of the U.S. Department of Health & Human Services (HHS).
Participant contact: 858-265-1711,