Colon & Rectal Cancers

At UC San Diego Health, we provide comprehensive care for colon and rectal cancers, combining advanced surgery, radiation therapy and chemotherapy into a treatment plan tailored to each patient.

As part of our Colorectal Cancer High-Risk Program, we also offer genetic testing to identify mutations or hereditary factors associated with colon cancers, empowering patients with valuable insights for prevention and treatment.

As part of our Colorectal Cancer High-Risk Program, we also offer genetic testing to look for mutations or genes associated with hereditary colon cancers.

Nationally Ranked Cancer Care

UC San Diego Health is proud to be ranked among the top 50 in the nation for cancer care and gastroenterology by U.S. News & World Report. We are also the only National Cancer Institute (NCI)-designated Comprehensive Cancer Center in San Diego County — the highest distinction for a U.S. cancer center. This designation means you'll benefit from the most advanced care, backed by research showing improved patient outcomes at NCI-designated centers.

Our colorectal cancer program is accredited by both the Commission on Cancer (CoC) and the National Accreditation Program for Rectal Cancer (NAPRC), underscoring our commitment to excellence and providing the best possible outcomes for patients with colon and rectal cancers.

Comprehensive, Personalized Treatments for Colon and Rectal Cancers

At your first visit, you will usually meet with your surgeon first to discuss what our pathologists have found about your cancer and review recommendations and options for treatment. Depending on your personalized care plan, you may be referred to a radiation oncologist, medical oncologist, or another cancer specialist.

Minimally Invasive Surgery

Expect the highest quality of surgical care from UC San Diego Health. Our surgeons were the first in the region to perform minimally invasive surgery for colorectal cancer. With our surgical expertise, you’re likely to experience less scarring, less pain and a faster recovery. 

Treatment of Early Stage Cancer

The majority of our colon cancer patients undergo minimally invasive surgery, including:

• Removal of small polyps during a colonoscopy
• Removal of large polyps through an endoscopic mucosal resection
• Laparoscopic surgery, including TAMIS (transanal minimally invasive surgery), which combines single-incision laparoscopic methods with transanal endoscopic microsurgery

Surgery for Metastatic Colon Cancer

For metastatic colon cancer, your surgeon may recommend a colectomy, a procedure to remove all or part of the colon. Cancer that has spread to the liver may also be removed. If cancer is found in the abdominal cavity (locally advanced carcinomatosis), you may be a candidate for heated intraperitoneal chemotherapy (HIPEC), a highly effective procedure used at only the leading cancer centers.

For advanced rectal cancer, a proctectomy may be necessary to remove all or part of the rectum. Depending on the stage of your cancer, you may be given chemotherapy and radiation before surgery. 

Radiation Therapy

Your treatment plan includes radiation therapy. UC San Diego Health's radiation oncology practice is integrated with the surgery and medical oncology practices within Moores Cancer Center. 

We offer the latest precision technologies in therapeutic radiation, and our radiation oncologists are national leaders in developing and translating new treatment techniques. 

Immunotherapy and Targeted Molecular Therapy 

Our understanding of cancer, including how genetics contribute to disease, is advancing rapidly. Depending on your cancer, you may be able to receive immunotherapy or targeted molecular therapy as part of your care.

Genetic testing may be used to predict your response to a certain treatment and select the best therapy for your tumor type.