Depression Treatment

If you are struggling with severe depression, you are not alone.

Depression affects about 20 million adults in America each year. About one-third will not find relief from antidepressant medications and talk therapy.

If you are one of these people, we can help. UC San Diego Health's Interventional Psychiatry Clinic offers brain stimulation therapy, also known as neuromodulation, for adults ages 18 and older who have treatment-resistant depression.

Neuromodulation uses magnetic or electrical stimulation to regulate or normalize brain activity. Our clinic focuses on treating depression with an innovative and advanced form of brain stimulation, known as transcranial magnetic stimulation (TMS). 

What Is Treatment-Resistant Depression?

Treatment-resistant depression is depression that is hard to treat. You likely have treatment-resistant depression if your medications are well managed but you have not responded sufficiently to at least two different antidepressants. TMS is currently only offered to patients with treatment-resistant depression.

Expert Mental Health Care

Our clinic is led by Zafiris "Jeff" Daskalakis, MD, PhD, an international expert in brain stimulation who oversees patient treatment protocols. Under his guidance, you receive the most effective and advanced TMS approaches for your depression. You won't find a higher level of expertise in brain stimulation therapies anywhere in the United States.

Personalized Treatment Plans

Your treatment plan is crafted using the best available medical science and an understanding of how the brain works. Your care plan is both targeted and personalized to your particular response.

Behavioral Health Plans Accepted

We accept behavioral health insurance and most insurance plans that are offered to UC San Diego Health employees. You're encouraged to verify that UC San Diego Health is an in-network provider.

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Research & Clinical Trials

Innovations in Treatments for Psychiatric Disorders

UC San Diego Health is leading innovations in treatments for psychiatric disorders. If you are interested in participating in a clinical trial or research study, talk to your UC San Diego Health provider.

Emergency Help Available 24/7

For a mental health emergency, call 911 or go to the nearest emergency room. You can also call the San Diego Crisis Line at 888-724-7240 for confidential, free support.

UC San Diego Health Emergency Departments

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