Translate this website into the following languages:

Close Tab
UC San Diego Health
menu iconMenu
search iconSearch

Non-Invasive Technology Evaluated to Treat Cardiac Chest Pain


May 14, 2010  |  

Pilot study to assess safety of painless shock wave technology for angina

UC San Diego Health System is enrolling a small group of patients in a two-year study to examine the safety of a non-invasive cardiac shock wave procedure for patients with chest pain caused by insufficient blood flow to the heart. 

Angina pectoris is a debilitating form of pain that affects more than ten million people in the U.S., according to the American Heart Association. Traditional angina treatments include drug therapy, angioplasty and coronary artery bypass graft surgery. Despite these therapies, many patients continue to experience the squeezing pain or pressure of continual angina pectoris. 

Cardiac shock wave technology sends low-intensity energy to specific areas of the heart to stimulate the growth of new blood vessels and relieve pain. It uses technology similar to, but of lower strength than Extracorporeal Shock Wave Lithotripsy (ESWL) that is used in the treatment of kidney stones.

Cardiac Shock Wave Therapy

UC San Diego Medical Center is evaluating non-invasive shock wave technology for the treatment of angina.

“These acoustic shock waves are not dissolving plaque in the same way that lithotripsy breaks up a stone,” said Anthony DeMaria, MD, cardiologist and principal investigator of the clinical trial at UC San Diego Medical Center. “Instead, these waves energize the heart tissue to release substances which, in turn, stimulate the formation of new blood vessels in the heart.”

The shock wave schedule consists of three 20-minute sessions per week over nine weeks. Patients who participate in this study will be evaluated at two and four-month intervals after the last treatment. Evaluations include a physical exam, treadmill tests, blood work, a drug induced stress/rest test, and a discussion of any adverse events or complications.

“This potential therapeutic approach is an alternative for patients who continue to have chest pain from angina, even though they take medicine, and are not candidates for a stent or bypass operation,” said DeMaria, associate dean for Outreach and Development for Health Sciences at UC San Diego and editor-in-chief of the Journal of the American College of Cardiology.

A maximum of 15 U.S. patients will be evaluated in this multicenter Phase I trial sponsored by Medispec Ltd., to assess the safety of Cardiospec™ Extracorporeal Shockwave Myocardial Revascularization (ESMR).

For more information, please contact Muppy Haigler, Research Study Coordinator at 619-543-6678 or

# # #

Media Contact: Jackie Carr, 619-543-6163,

Related Specialties

Media Contact

Share This Article

Related News

While astronauts on long space missions do not experience a change in spinal disc height, the muscles supporting the spine weaken, find researchers at University of California San Diego School of Medi ...
There are many unanswered questions about the mechanisms that contribute to the onset of type 1 diabetes. Researchers at University of California San Diego School of Medicine hope to answer some of th ...
Viruses hijack the molecular machinery in human cells to survive and replicate, often damaging those host cells in the process. Researchers at the University of California San Diego School of Medicine ...
Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic materia ...

Follow Us

Our bimonthly newsletter delivers healthy lifestyle tips, patient stories and research discovery news. Subscribe: