Lymphangioleiomyomatosis (LAM) Program

Our Lymphangioleiomyomatosis (LAM) Clinic is certified by the LAM Foundation. This distinction recognizes our program's dedication to the care, advancement of research, and treatments for individuals with LAM.

Our LAM program is led by physicians who are nationally recognized experts in this condition.

Lung Disease & Respiratory Care

What is Lymphangioleiomyomatosis?

LAM is a progressive lung disease that usually strikes women during their childbearing years. It is caused by the release of abnormal growth of smooth muscle cells (LAM cells).

The LAM cells invade lung tissues, including the airways, and blood and lymph vessels. Over time, the cells form bundles in the walls of the airways, as well as the blood and lymph vessels, causing them to become obstructed. These cells produce materials that break down tissue, causing the formation of cysts.

LAM affects each woman differently. Some women have no symptoms and do not develop complications. In others, symptoms can relate to the lung, kidney and/or liver.

How is LAM Treated?

The UC San Diego Health Advanced Lung Disease Program offers patients with LAM both standard and cutting-edge investigational therapies. Standard treatment requires therapy with a drug that suppresses your immune system (sirolimus) along with close monitoring for complications related to LAM.

Innovation Through Research

Our clinical experts are actively involved in expanding horizons in the area of research for LAM. Some patients may be candidates for clinical trials offered at UC San Diego Health.

Learn more about clinical trials

A Team Approach

Because LAM can cause various organ involvement and is potentially progressive in nature, we use a multidisciplinary approach to this condition.

Our team partners with physicians and surgeons who have expertise in their respective specialties as they relate to LAM, including interventional radiologists, nephrologists, urologists, thoracic surgeons and the lung transplant team.

In addition to medical care, you can benefit from our services to improve your health and empower you with more knowledge of LAM. These include:

  • Pulmonary rehabilitation to improve breathing techniques and functional status
  • Smoking cessation counseling
  • Nutritional education and services provided by registered dietitians

Want to Quit Smoking?

We can help.

Whether you're ready to quit or just thinking about it, learn more about smoking cessation or call 800-NO-BUTTS.