Translate
Translate this website into the following languages:



Close Tab
Donations
UC San Diego Health
menu iconMenu
search iconSearch

Botox Injections Now Used for Severe Urinary Incontinence

 

March 13, 2012  |  

When you think of Botox injections, you probably think of getting rid of unwanted wrinkles around the eyes or forehead, but recently the US Food and Drug Administration (FDA) approved using the injections to help patients with neurological conditions who suffer from incontinence, or an overactive bladder. 

Botox injections paralyze the bladder muscle to prevent contractions that cause urgency to urinate or leak.  Although medications and behavioral modifications are treatment options, many patients, especially the elderly, do not respond to these methods and need a more aggressive approach.

Charles Nager 
Charles Nager, MD, co-director of the UC San Diego Women’s Pelvic Medicine Center at UC San Diego Health System.
“About 80 percent of patients with neurological conditions, such as spinal cord injuries, Parkinson’s disease and multiple sclerosis, see improvement after about a week, and the results can last four to nine months,” said Charles Nager, MD, co-director of the UC San Diego Women’s Pelvic Medicine Center at UC San Diego Health System.

Incontinence is the seventh condition, including chronic migraines and underarm sweating, that Botox has been approved to treat since the drug first arrived on the market as a wrinkle reducer in 2002. 

The outpatient procedure uses a local numbing gel, followed by 15 to 20 injections in different areas of the bladder muscle. 

“It can really be life changing for someone with severe incontinence issues,” said Nager who also serves as director of Urogynecology and Reconstructive Pelvic Surgery in the Department of Reproductive Medicine at UC San Diego. 

UC San Diego Health System is currently recruiting for a clinical trial to test Botox injections versus sacral nerve stimulation as incontinence treatment options.

Sacral nerve stimulation uses small, electrical impulses to the nerves that control urination.  The impulses are generated by a small device surgically placed under the skin.  Attached to the device is a thin, electrode-tipped wire that passes under the patient’s skin, carrying impulses to the sacral nerve.  The surgery is an outpatient procedure done under local anesthesia.

Patients involved in the clinical trial are required to have tried two drugs that previously failed to treat their incontinence issues. 

For more information on the upcoming clinical trial, please visit: health.ucsd.edu/clinicaltrials

# # #

Media Contact: Jackie Carr, 619-543-6163, jcarr@ucsd.edu




Media Contact

Share This Article


Related News

2/22/2017
University of California San Diego School of Medicine researchers screened 10,000 colonies of bacteria found on the epidermis to determine how many had antimicrobial properties and at what rate these ...
2/17/2017
An international research team, led by principal investigator Elizabeth A. Winzeler, PhD, professor in the pediatric division of host-microbe systems and therapeutics at University of California San D ...
2/16/2017
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial scourge that is resistant to most common antibiotics and thus difficult to treat, particularly in children where it commonly causes co ...
2/15/2017
A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has developed a new tool to analyze an often overlooked aspect of cancer genetics — an alteratio ...



Follow Us

Our bimonthly newsletter delivers healthy lifestyle tips, patient stories and research discovery news. Subscribe: